Evaluation of Hormone Quantification as an Orientation Screening in the Diagnosis of Hormone-Dependent Breast Cancers in Women in Abidjan, Côte d'Ivoire

Aim: Estrogens and progesterone are essential for breast development in women. Paradoxically they promote the of cancer, through stimulation proliferation cells by action hormone receptors. In Côte d'Ivoire, more than half all diagnosed cases cancer hormone-dependent. Because link between female hormones consideration certain factors, such as period influence (estrogen progesterone) well their quantification, could be considered orientation screening hormone-dependent cancer.
 Methodology: A case-control study conducted at Cancerology Department Treichville University Hospital, National Blood Transfusion Centre, Pasteur Institute d'Ivoire recruited 85 participants, including 39 46 non-menopausal menopausal controls. Socio-demographic information participants' clinical status were collected a questionnaire consultation medical file. samples taken dry red tubes with coagulation activator on day inclusion postmenopausal women during follicular phase (between days 4 7 menstrual cycle). The quantification (estrogen, progesterone, FSH, LH) was performed immunoassay Cobas e411 Analyser®.
 Results: Postmenopausal had early menarche (13 years) late menopause (52.46 compared to controls also slightly higher mean plasma oestradiol 2 levels (P=0.04; P=0.017). Among these cases, those ER+ tumors oestradiol-2 (15.28 pg/mL) ER- (9.20 (P=0.03).
 Conclusion: epidemiological investigation blood revealed positive association hormones, concentrations,